• The Stem cell protocols: From laboratory to applications

    Cancer stem cells: Isolation and Culture


    The past twenty years have seen a significant worldwide reduction in mortality from cancers, largely due to improved early detection methods and develop- ment of more effective therapies, including adjuvant therapies. However, more than fifty percent of tumors do not respond to these therapies and more than seventy percent of patients relapse after five years. These failures are largely due to cancer stem cells (CSCs), found in all...

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  • The Stem cell protocols: From laboratory to applications

    Mesenchymal stem cell assays


    Mesenchymal stem cell assays is the new title under the book series Stem Cell Protocols that publish all protocols related to isolation, characterization, application of stem cells in vitro, preclinical and clinical trials. 

    Mesenchymal stem cells now become popular stem cells used in the clinic. With more than 25 years from the first clinical case of mesenchymal stem cell transplantation, mesenchymal stem cells have been transplanted to treat more than 50 kinds of diseases. Particularly, recently up tp 5 mesenchymal stem cell-based drugs were approved by FDA in various...

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  • The Anti-tumor drug discovery protocols: From in vitro to in vivo

    Tumor Animal Models: Methods-Protocols


    Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results.
    Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An...

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New Releases

Cover for Cell Cytotoxicity Assay: In vitro Assays Cell Cytotoxicity Assay: In vitro Assays
Matthie Robert, Phuc Van Pham
April 16, 2016


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