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Mesenchymal Stem Cell Assays: Characterization and Authentication
Clinical applications of mesenchymal stem cells (MSCs) rapidly growth in recent years. Besides, transplantation of non-cultured mesenchymal stem cells in forms of mononuclear cells, stromal vascular fraction, cultured mesenchymal stem cells were applied in clinic. Particularly, some cultured mesenchymal stem cells based drugs approved by Canada, Korea... pushed MSCs into treatment.
However, the big issues related to cultured MSCs are some possible changes in MSCs' phenotypes as well as MSCs' genome. Therefore, MSCs should be evaluated about characterization, properties, genome stability, differentiation, sefl-renewal...
This book is published under book series "Stem Cell Protocols" to provide popular protocols to characterize MSCs.