Mesenchymal Stem Cell Assays: Characterization and Authentication

Authors

Phuc Van Pham
Laboratory of Stem Cell Research and Application, HCMUS, VNU-HCM

Synopsis

Clinical applications of mesenchymal stem cells (MSCs) rapidly growth in recent years. Besides, transplantation of non-cultured mesenchymal stem cells in forms of mononuclear cells, stromal vascular fraction, cultured mesenchymal stem cells were applied in clinic. Particularly, some cultured mesenchymal stem cells based drugs approved by Canada, Korea... pushed MSCs into treatment.

However, the big issues related to cultured MSCs are some possible changes in MSCs' phenotypes as well as MSCs' genome. Therefore, MSCs should be evaluated about characterization, properties, genome stability, differentiation, sefl-renewal...

This book is published under book series "Stem Cell Protocols" to provide popular protocols to characterize MSCs.

 

Author Biography

Phuc Van Pham, Laboratory of Stem Cell Research and Application, HCMUS, VNU-HCM

Phuc Van Pham received his Ph.D. in Human Physiology from Vietnam National University, Vietnam in 2007. He is currently a Professor of Biology at the University of Science, Vietnam National University in Ho Chi Minh City, Vietnam and Acting Director of the Laboratory of Stem Cell Research and Application. He is a longstanding lecturer and translational scientist at the University, and is a member of several societies and journal editorial boards focused on stem cells.

Dr. Pham and his colleagues have established one of the first multidisciplinary stem cell centers in Vietnam, and he has successfully launched an array of technologies in stem cell isolations. His research interests include stem cell isolation, stem cell therapy, mesenchymal stem cells, cancer stem cells, immunotherapy and regenerative medicine. He has published extensively in these areas.

After many years of experience as an embryologist, cell biologist, and molecular biologist, collaborating with leading researchers in Singapore, Japan, and the United States, Dr. Pham is a student again, keen to reach beyond the traditional boundaries of biology.

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